DV1
DV1 is a selective antagonist for CXC chemokine receptor 4 (CXCR4) . DV1 exhibits antiviral activity by blocking HIV-1 entry through the CXCR4 co-receptor. DV1 is stable in rat plasma and exhibits good pharmacokinetic characteristics in rat models[1].
Product Specifications
UNSPSC
12352209
Target
CXCR; HIV
Type
Peptides
Related Pathways
Anti-infection; GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dv1.html
Smiles
O=C(NCC(N[C@H](C)C(N[C@H](CO)C(N[C@H](CC1=CNC2=CC=CC=C12)C(N[C@H](CC3=CNC=N3)C(N[C@H](CCCNC(N)=N)C(N4[C@@H](CCC4)C(N[C@H](CC(O)=O)C(N[C@H](CCCCN)C(N[C@H](CS)C(N[C@H](CS)C(N[C@H](CC(C)C)C(NCC(N[C@H](CC5=CC=C(C=C5)O)C(N[C@H](CCC(N)=O)C(N[C@H](CCCCN)C(N[C@H](CCCNC(N)=N)C(N6[C@@H](CCC6)C(N[C@H](CC(C)C)C(N7[C@H](CCC7)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@@H](CC(C)C)N
Molecular Formula
C108H170N34O26S2
Molecular Weight
2424.85
References & Citations
[1]Zhu Y, et al., LC-MS/MS assay for the determination of a novel D-peptide antagonist of CXCR4 in rat plasma and its application to a preclinical pharmacokinetic study. J Pharm Biomed Anal. 2018 Nov 30;161:159-167.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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