Infigratinib-Boc
Product Specifications
UNSPSC Description
Infigratinib-Boc is a derivative of Infigratinib containing a Boc (t-Butyloxy carbonyl) group. Infigratinib is an ATP-competitive pan-FGFR inhibitor[1].
Target Antigen
FGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/infigratinib-boc.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=C(Cl)C(OC)=CC(OC)=C1Cl)N(C)C2=CC(NC(C=C3)=CC=C3N4CCN(C(OC(C)(C)C)=O)CC4)=NC=N2
Molecular Weight
632.54
References & Citations
[1]Guangyan Du, et al. Discovery of a Potent Degrader for Fibroblast Growth Factor Receptor 1/2. Angew Chem Int Ed Engl. 2021 Jul 12;60(29):15905-15911.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-160124/Infigratinib-Boc-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-160124/Infigratinib-Boc-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2504949-83-9
Available Sizes
Curated Selection
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