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Infigratinib-Boc

Infigratinib-Boc is a derivative of Infigratinib containing a Boc (t-Butyloxy carbonyl) group. Infigratinib is an ATP-competitive pan-FGFR inhibitor[1].

Product Specifications

CAS Number

[2504949-83-9]

UNSPSC

12352005

Target

FGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/infigratinib-boc.html

Purity

98.29

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NC1=C(Cl)C(OC)=CC(OC)=C1Cl)N(C)C2=CC(NC(C=C3)=CC=C3N4CCN(C(OC(C)(C)C)=O)CC4)=NC=N2

Molecular Formula

C29H35Cl2N7O5

Molecular Weight

632.54

References & Citations

[1]Guangyan Du, et al. Discovery of a Potent Degrader for Fibroblast Growth Factor Receptor 1/2. Angew Chem Int Ed Engl. 2021 Jul 12;60 (29) :15905-15911.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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