FABP4/5-IN-5
FABP4/5-IN-5 (compound D9) is a potent inhibitor of FABP4 and FABP5, with the IC50s of 4.68 μM and 10.72 μM, respectively.FABP4/5-IN-5 plays an important role in metabolism disorder like diabetes mellitus[1].
Product Specifications
CAS Number
[2862791-11-3]
UNSPSC
12352005
Target
FABP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/fabp4-5-in-5.html
Purity
98.10
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(NS(=O)(C2=CC=C(C3=C2C=CC=C3)C4=C(Cl)C=C(F)C=C4)=O)=CC=C1F)O
Molecular Formula
C23H14ClF2NO4S
Molecular Weight
473.88
References & Citations
[1]Yu-Long He, et al. Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus. Eur J Med Chem. 2021 Nov 15:224:113720.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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