FABP4/5-IN-5

FABP4/5-IN-5 (compound D9) is a potent inhibitor of FABP4 and FABP5, with the IC50s of 4.68 μM and 10.72 μM, respectively.FABP4/5-IN-5 plays an important role in metabolism disorder like diabetes mellitus[1].

Product Specifications

CAS Number

[2862791-11-3]

UNSPSC

12352005

Target

FABP

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/fabp4-5-in-5.html

Purity

98.10

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=C(C1=CC(NS(=O)(C2=CC=C(C3=C2C=CC=C3)C4=C(Cl)C=C(F)C=C4)=O)=CC=C1F)O

Molecular Formula

C23H14ClF2NO4S

Molecular Weight

473.88

References & Citations

[1]Yu-Long He, et al. Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus. Eur J Med Chem. 2021 Nov 15:224:113720.