DCG04

DCG04 is a multivalent ligand for the mannose-6-phosphate receptor. DCG-04 is an activity-based probe for cysteine cathepsins, and can be used for labelling numerous cysteine cathepsins in cell and tissue lysates[1][2].

Product Specifications

CAS Number

[314263-42-8]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dcg04.html

Purity

98.55

Solubility

DMSO : 3.33 mg/mL (ultrasonic)

Smiles

OC(C=C1)=CC=C1C[C@@H](C(NCCCCCC(N[C@H](C(N)=O)CCCCNC(CCCC[C@H]2[C@]3([H])[C@](NC(N3)=O)([H])CS2)=O)=O)=O)NC([C@H](CC(C)C)NC([C@@H]4[C@H](O4)C(OCC)=O)=O)=O

Molecular Formula

C43H66N8O11S

Molecular Weight

903.10

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Hillaert U, et al. Receptor-mediated targeting of cathepsins in professional antigen presenting cells [published correction appears in Angew Chem Int Ed Engl. 2009;48 (14) :2442.. Saragliadis, Anastasios [corrected to Saragliadis, Athanasios]]. Angew Chem Int Ed Engl. 2009;48 (9) :1629-1632. |[2]Paulick MG, et al. Development of activity-based probes for cathepsin X. ACS Chem Biol. 2011;6 (6) :563-572.