Efletirizine
Efletirizine (EFZ) is an orally active antihistamine with high selectivity and affinity to the H1-receptor. Efletirizine can be used for allergic disease research[1].
Product Specifications
CAS Number
150756-35-7
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/efletirizine.html
Solubility
10 mM in DMSO
Smiles
OC(COCCN(CC1)CCN1C(C2=CC=C(F)C=C2)C3=CC=C(F)C=C3)=O
Molecular Formula
C21H24F2N2O3
Molecular Weight
390.42
References & Citations
[1]Coe RA, et al. Quantitation of efletirizine in human plasma and urine using automated solid-phase extraction and column-switching high-performance liquid chromatography. J Chromatogr B Biomed Sci Appl. 1999 Jul 9;730 (2) :239-47.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
H1 Receptor
Available Sizes
Frequently Asked Questions
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