Efletirizine

Efletirizine (EFZ) is an orally active antihistamine with high selectivity and affinity to the H1-receptor. Efletirizine can be used for allergic disease research[1].

Product Specifications

CAS Number

[150756-35-7]

UNSPSC

12352005

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/efletirizine.html

Solubility

10 mM in DMSO

Smiles

OC(COCCN(CC1)CCN1C(C2=CC=C(F)C=C2)C3=CC=C(F)C=C3)=O

Molecular Formula

C21H24F2N2O3

Molecular Weight

390.42

References & Citations

[1]Coe RA, et al. Quantitation of efletirizine in human plasma and urine using automated solid-phase extraction and column-switching high-performance liquid chromatography. J Chromatogr B Biomed Sci Appl. 1999 Jul 9;730 (2) :239-47.