Acetaminophen metabolite 3-hydroxy-acetaminophen

Acetaminophen metabolite 3-hydroxy-acetaminophen (3-Hydroxyacetaminophen) is a non-toxic metabolite and antioxidant of acetaminophen (HY-66005) with free radical scavenging activity. Acetaminophen metabolite 3-hydroxy-acetaminophen can reduce oxidative damage by exerting electron donation ability and antioxidant activity through phenolic hydroxyl groups. 3-hydroxy-acetaminophen can be used to study the toxicity mechanism and drug metabolism of acetaminophen[1][2].

Product Specifications

CAS Number

[37519-14-5]

Product Name Alternative

3-Hydroxyacetaminophen

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Acetaminophen-metabolite-3-hydroxy-acetaminophen.html

Concentration

10mM

Purity

99.76

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

OC1=C(O)C=C(NC(C)=O)C=C1

Molecular Formula

C8H9NO3

Molecular Weight

167.16

Precautions

H302, H315, H319, H335

References & Citations

[1]Hazai E, et al. Reduction of toxic metabolite formation of acetaminophen. Biochem Biophys Res Commun. 2002 Mar 8;291 (4) :1089-94.|[2]Borges, et al. A theoretical study for oxidative metabolism of acetaminophen. Journal of Computational and Theoretical Nanoscience 7.10 (2010) : 1968-1972.