Oleacein
Oleacein (Compound 9) is an ACE inhibitor that can be isolated from J. grandiflorum. Oleacein is orally active and can be used in the study of metabolic and cardiovascular diseases[1][2].
Product Specifications
CAS Number
[149183-75-5]
UNSPSC
12352005
Target
Angiotensin-converting Enzyme (ACE)
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/oleacein.html
Purity
90
Solubility
10 mM in DMSO
Smiles
C/C=C(C=O)\[C@@H](CC=O)CC(OCCC1=CC=C(O)C(O)=C1)=O
Molecular Formula
C17H20O6
Molecular Weight
320.34
References & Citations
[1]Somanadhan B, et al. Angiotensin converting enzyme (ACE) inhibitors from Jasminum azoricum and Jasminum grandiflorum. Planta Med. 1998 Apr;64 (3) :246-50.|[2]Lombardo GE, et al. Effects of Oleacein on High-Fat Diet-Dependent Steatosis, Weight Gain, and Insulin Resistance in Mice.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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