Beta-Phosphoglucomutase

<strong>beta-Phosphoglucomutase </strong> <strong>Catalog number:</strong> B2020186 <strong>Lot number:</strong> Batch Dependent <strong>Expiration Date:</strong> Batch dependent <strong>Amount:</strong> 1 kU <strong>Molecular Weight or Concentration:</strong> 34 kDa <strong>Supplied as:</strong> Lyophilized <strong>Applications:</strong> a molecular tool for various biochemical applications <strong>Storage:</strong> -20C <strong>Keywords:</strong> _PGM-EP, _-D-Glucose 1,6-phosphomutase <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. <strong>References:</strong> 1: Buckley AA, Faustoferri RC, Quivey RG. _-Phosphoglucomutase contributes to aciduricity in Streptococcus mutans Microbiology (Reading). 2014 Apr;160(Pt 4):818-827. 2: Carroll-Poehls M, Jakeman DL. Synthesis of a novel fluorinated phosphonyl C-glycoside, (3-deoxy-3-fluoro-_-d-glucopyranosyl)methylphosphonate, a potential inhibitor of _-phosphoglucomutase Carbohydr Res. 2023 Dec;534:108979. 3: Ghosh R, Jakeman DL. A novel bis-phosphonyl C-glycoside: the first synthesis of C-(1,6-deoxy-_-D-glucopyranosyl)dimethylphosphonate, a stable bisphosphonate to probe the mechanism of _-phosphoglucomutase Org Biomol Chem. 2025 Jan 29;23(5):1129-1135. 4: Zhang H, Zhang M, Zhu K, Feng Y, Yang L, Ding W. Unraveling the mechanism: How does _-phosphoglucomutase from the haloacid dehalogenase superfamily catalyze the interconversion of _-d-glucose 1-phosphate and _-d-glucose 6-phosphate? A chemical perspective J Inorg Biochem. 2025 Mar;264:112794. 5: Singh L, Karthikeyan S, Thakur KG. Biochemical and structural characterization reveals Rv3400 codes for _-phosphoglucomutase in Mycobacterium tuberculosis Protein Sci. 2024 Apr;33(4):e4943. 6: Zhang G, Dai J, Wang L, Dunaway-Mariano D, Tremblay LW, Allen KN. Catalytic cycling in beta-phosphoglucomutase: a kinetic and structural analysis Biochemistry. 2005 Jul 12;44(27):9404-16. 7: Barrozo A, Liao Q, Esguerra M, Marloie G, Florián J, Williams NH, Kamerlin SCL. Computer simulations of the catalytic mechanism of wild-type and mutant _-phosphoglucomutase Org Biomol Chem. 2018 Mar 28;16(12):2060-2073. 8: Cruz-Navarrete FA, Baxter NJ, Flinders AJ, Buzoianu A, Cliff MJ, Baker PJ, Waltho JP. Peri active site catalysis of proline isomerisation is the molecular basis of allomorphy in _-phosphoglucomutase Commun Biol. 2024 Jul 27;7(1):909. 9: Griffin JL, Bowler MW, Baxter NJ, Leigh KN, Dannatt HR, Hounslow AM, Blackburn GM, Webster CE, Cliff MJ, Waltho JP. Near attack conformers dominate _-phosphoglucomutase complexes where geometry and charge distribution reflect those of substrate Proc Natl Acad Sci U S A. 2012 May 1;109(18):6910-5. <a href="https://pubmed.ncbi.nlm.nih.gov/16784233">10: Dai J, Wang L, Allen KN, Radstrom P, Dunaway-Mariano D. Conformational cycling in beta-phosphoglucomutase catalysis: reorientation of the beta-D-glucose 1,6-(Bis)phosphate intermediate Biochemistry. 2006 Jun 27;45(25):7818-24. </a> <br><strong>Products Related to beta-Phosphoglucomutase can be found at</strong> <a href="https://moleculardepot.com/product-category/Enzymes/"> Enzymes</a>