Human CDC34 Protein

<strong>Human CDC34 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011899_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> UBCH3 protein, UBE2R1, CDC-34, CDC 34, CDC34, CDC 34 protein, CDC-34 protein, Ubiquitin-conjugating enzyme E2 R1 protein, E2-CDC34 protein, UBC3 protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Liu HT, Liu S, Liu L, Ma RR, Gao P. EGR1-Mediated Transcription of lncRNA-HNF1A-AS1 Promotes Cell-Cycle Progression in Gastric Cancer Cancer Res. 2018 Oct 15;78(20):5877-5890._x000D_ 2: Harper JW, Schulman BA. Cullin-RING Ubiquitin Ligase Regulatory Circuits: A Quarter Century Beyond the F-Box Hypothesis Annu Rev Biochem. 2021 Jun 20;90:403-429._x000D_ 3: Choi YS, Wu K, Jeong K, Lee D, Jeon YH, Choi BS, Pan ZQ, Ryu KS, Cheong C. The human Cdc34 carboxyl terminus contains a non-covalent ubiquitin binding activity that contributes to SCF-dependent ubiquitination J Biol Chem. 2010 Jun 4;285(23):17754-62._x000D_ 4: Lisztwan J, Marti A, Sutterlüty H, Gstaiger M, Wirbelauer C, Krek W. Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway EMBO J. 1998 Jan 15;17(2):368-83._x000D_ 5: Gazdoiu S, Yamoah K, Wu K, Escalante CR, Tappin I, Bermudez V, Aggarwal AK, Hurwitz J, Pan ZQ. Proximity-induced activation of human Cdc34 through heterologous dimerization Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15053-8._x000D_ 6: Block K, Appikonda S, Lin HR, Bloom J, Pagano M, Yew PR. The acidic tail domain of human Cdc34 is required for p27Kip1 ubiquitination and complementation of a cdc34 temperature sensitive yeast strain Cell Cycle. 2005 Oct;4(10):1421-7._x000D_ 7: Pati D, Meistrich ML, Plon SE. Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysis Mol Cell Biol. 1999 Jul;19(7):5001-13._x000D_ 8: Butz N, Ruetz S, Natt F, Hall J, Weiler J, Mestan J, Ducarre M, Grossenbacher R, Hauser P, Kempf D, Hofmann F. The human ubiquitin-conjugating enzyme Cdc34 controls cellular proliferation through regulation of p27Kip1 protein levels Exp Cell Res. 2005 Feb 15;303(2):482-93._x000D_ 9: Gazdoiu S, Yamoah K, Wu K, Pan ZQ. Human Cdc34 employs distinct sites to coordinate attachment of ubiquitin to a substrate and assembly of polyubiquitin chains Mol Cell Biol. 2007 Oct;27(20):7041-52._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/11546811">10: Block K, Boyer TG, Yew PR. Phosphorylation of the human ubiquitin-conjugating enzyme, CDC34, by casein kinase 2 J Biol Chem. 2001 Nov 2;276(44):41049-58. </a>_x000D_ _x000D_ <strong>Products Related to Human CDC34 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>