What is the catalog number for HyT36?

The catalog number for HyT36 is HY-141676.

What sizes are available for HyT36?

HyT36 is available in the following size(s): 5 mg, 10 mM - 1 mL, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does HyT36 come in?

HyT36 is available in 6 different pack sizes.

HyT36 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HyT36?

HyT36 is manufactured by QuantiMol.

What is the estimated delivery time for HyT36?

Estimated delivery time for HyT36 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HyT36?

The safety data sheet for HyT36 is available here: http://file.medchemexpress.com/batch_PDF/HY-141676/HyT36-SDS-MedChemExpress.pdf.

HyT36

HyT36 is a low molecular weight hydrophobic tag that promotes the degradation of fusion protein and pseudokinase Her3[1][2][3].

Product Specifications

CAS Number

1323151-45-6

UNSPSC

12352211

Target

EGFR

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/hyt36.html

Purity

96.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

ClCCCCCCOCCOCCNC([C@H](C)CCC1(C[C@H]2C3)C[C@H]3C[C@H](C2)C1)=O

Molecular Formula

C25H44ClNO3

Molecular Weight

442.07

References & Citations

[1]Tae HS, et al. Identification of hydrophobic tags for the degradation of stabilized proteins. Chembiochem. 2012 Mar 5;13 (4) :538-41.|[2]Rubner S, et al. Poloxin-2HT+: changing the hydrophobic tag of Poloxin-2HT increases Plk1 degradation and apoptosis induction in tumor cells. Org Biomol Chem. 2019 Mar 20;17 (12) :3113-3117. |[3]Neklesa TK, et al. A bidirectional system for the dynamic small molecule control of intracellular fusion proteins. ACS Chem Biol. 2013 Oct 18;8 (10) :2293-2300.