Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Daurisoline-d5

Daurisoline-d5 is the deuterium labeled Daurisoline. Daurisoline is a bis-benzylisoquinoline alkaloid that can be isolated from Menispermum dauricum and Rhizoma Menispermi. Daurisoline exerts a blocking effect on hERG and has antiarrhythmic effects. Daurisoline is a potent autophagy blocker that can be used for the research of cancer[1][2].

Product Specifications

Product Name Alternative

(R, R) -Daurisoline-d5

UNSPSC

12352005

Target

Autophagy; Isotope-Labeled Compounds; Potassium Channel

Type

Isotope-Labeled Compounds

Related Pathways

Autophagy; Membrane Transporter/Ion Channel; Others

Applications

COVID-19-immunoregulation

Field of Research

Cancer

Solubility

10 mM in DMSO

Smiles

OC1=C([2H])C2=C(C([2H])=C1OC)CCN(C)[C@@H]2CC3=CC([2H])=C(O)C(OC4=CC=C(C[C@H]5N(C)CCC6=C5C([2H])=C(OC)C(OC)=C6[2H])C=C4)=C3

Molecular Formula

C37H37D5N2O6

Molecular Weight

615.77

References & Citations

[1]Liu Q, et al. Effect of daurisoline on HERG channel electrophysiological function and protein expression. J Nat Prod. 2012 Sep 28;75 (9) :1539-45.|[2]Wu MY, et al. Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity. Oncotarget. 2017 Sep 8;8 (44) :77673-77684.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Hepatocyte Specific (HepPar1), 1mg/mL
BNUM0966-50 1x 50 µL

Hepatocyte Specific (HepPar1), 1mg/mL

Sign In for Pricing
View Details
Tissue FFPE Sections, Kidney
CS703181 5x 5 µm

Tissue FFPE Sections, Kidney

Sign In for Pricing
View Details
hHR23b (RAD23B) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI9F8]
TA804863BM 100 µL

hHR23b (RAD23B) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI9F8]

Sign In for Pricing
View Details
Pre and Post Vacuum Class B Autoclave BAPV-202
BAPV-202 1 Unit

Pre and Post Vacuum Class B Autoclave BAPV-202

Sign In for Pricing
View Details
Recombinant Human GDNF Protein (Fc Tag)
PDMH100264-01 20 µg

Recombinant Human GDNF Protein (Fc Tag)

Sign In for Pricing
View Details
Recombinant Human GDNF Protein (Fc Tag)
PDMH100264-02 100 µg

Recombinant Human GDNF Protein (Fc Tag)

Sign In for Pricing
View Details