DOTA-RBB-Ga
Product Specifications
UNSPSC Description
DOTA-RBB-Ga is a conjugate of a chelator DOTA, an inhibitor for CDK4/6 Ribociclib (HY-15777) and a gallium. DOTA-RBB-Ga can be used as a PET radiotracer for CDK4/6 positive tumor, when labeled with radioactive gallium 68Ga[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Smiles
O=C(N(C)C)C1=CC2=CN=C(NC3=NC=C(N4CCN(/C(CN5CCN(CC([O-]6)=O)CCN(CC([O-]7)=O)CCN(C8)CC5)=O/[Ga+3]76[O-]C8=O)CC4)C=C3)N=C2N1C9CCCC9
Molecular Weight
887.64
References & Citations
[1]Yu Z P, et al., Synthesis and Preclinical Evaluation of Novel 68Ga-DOTA-RBB as Potential PET Radiotracer for Imaging CDK4/6 in Tumors[J]. ACS Medicinal Chemistry Letters, 2024.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Curated Selection
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