2-Hydroxyphenylacetic acid

2-Hydroxyphenylacetic acid is a metabolite of Phenylalanine and Tyrosine, and is also a product of the biotransformation of Phenylacetonitrile by marine fungi. 2-Hydroxyphenylacetic acid can be used as a potential biomarker for food. 2-Hydroxyphenylacetic acid can be used in the study of phenylketonuria and related hyperphenylalaninemias[1][2][3].

Product Specifications

CAS Number

[614-75-5]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Drug Metabolite; Fungal

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/2-Hydroxyphenylacetic_acid.html

Purity

98.79

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C1=CC=CC(=C1CC(O)=O)O

Molecular Formula

C8H8O3

Molecular Weight

152.15

Precautions

H315, H319, H335

References & Citations

[1]Mönch E, et al. Examination of urine metabolites in the newborn period and during protein loading tests at 6 months of age--Part 1. Eur J Pediatr. 1990;149 Suppl 1:S17-24.|[2]de Oliveira JR, et al. Biotransformation of phenylacetonitrile to 2-hydroxyphenylacetic acid by marine fungi. Mar Biotechnol (NY) . 2013 Feb;15 (1) :97-103.|[3]Guo KH, et al. Cell-Based Biosensor with Dual Signal Outputs for Simultaneous Quantification of Phenylacetic Acid and Phenylethylamine. ACS Synth Biol. 2018 Dec 21;7 (12) :2790-2795.