MD6a
MD6a is a melatonin derivative with inhibitroy activity towards PARP-1, which maintains proteins hemostasis and improves mitochondrial function through TOR/HSF-1 signaling. MD6a a neuroprotective effect[1].
Product Specifications
UNSPSC
12352005
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/md6a.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(/C=C/C2=CC=CC=C2)=C(NC=C3CCNC(C)=O)C3=C1
Molecular Formula
C21H22N2O2
Molecular Weight
334.41
References & Citations
[1]Ma QW, et al., Melatonin derivative 6a as a PARP-1 inhibitor for the treatment of Parkinson's disease. Front Pharmacol. 2024 Feb 27;15:1363212.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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