H15-LOX-2 inhibitor 2
H15-LOX-2 inhibitor 2 (Compound 10) is an inhibitor of h15-LOX, with IC50 and Ki values of 26.9 μM and 16.4 μM, respectively[1].
Product Specifications
UNSPSC
12352005
Target
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/h15-lox-2-inhibitor-2.html
Smiles
CC1=CC=CN2C1=NC(N(C(C)C)C(C(C(NCC[NH+]3CCOCC3)=O)=C4)=[NH2+])=C4C2=O.[Cl-].[Cl-]
Molecular Formula
C22H30Cl2N6O3
Molecular Weight
497.42
References & Citations
[1]Viviani L G, et al. Identification of novel human 15-lipoxygenase-2 (h15-LOX-2) inhibitors using a virtual screening approach[J]. bioRxiv, 2024: 2024.07. 21.604444.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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