(Rac) -PEAQX
Selected Variant
HY-12294B-01
Size: 1 mg
(Rac) -PEAQX is a NMDA receptor agonist. (Rac) -PEAQX can promote the activation of caspase-3 and induce cell apoptosis in cortical striatal slice cultures [1].
Product Specifications
CAS Number
2514919-70-9
Product Name Alternative
(Rac) -NVP-AAM077
UNSPSC
12352005
Target
Apoptosis; Caspase; iGluR
Type
Reference compound
Related Pathways
Apoptosis; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rac-peaqx.html
Smiles
O=C1C(NC2=C(C(C(P(O)(O)=O)NC(C3=CC=C(Br)C=C3)C)=CC=C2)N1)=O
Molecular Formula
C17H17BrN3O5P
Molecular Weight
454.21
References & Citations
[1]Annabel Romero-Hernandez, et al. Novel Mode of Antagonist Binding in NMDA Receptors Revealed by the Crystal Structure of the GluN1-GluN2A Ligand-Binding Domain Complexed to NVP-AAM077. Mol Pharmacol
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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