Human Platelet Factor 4 Native

<strong>Human Platelet Factor 4 Native</strong>_x000D_ <strong>Catalog number:</strong> B2016964_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 27.1 kDa homotetramer (7.8 kDa subunits)_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80¬∞C_x000D_ <strong>Keywords:</strong> Platelet factor 4, C-X-C motif chemokine 4, CXCL4, Iroplact, Oncostatin-A, SCYB4_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Li N. Platelets as an inter-player between hyperlipidaemia and atherosclerosis J Intern Med. 2024 Jul;296(1):39-52._x000D_ 2: Gewirtz AM, Calabretta B, Rucinski B, Niewiarowski S, Xu WY. Inhibition of human megakaryocytopoiesis in vitro by platelet factor 4 (PF4) and a synthetic COOH-terminal PF4 peptide J Clin Invest. 1989 May;83(5):1477-86._x000D_ 3: Niu C, Yang Y, Huynh A, Nazy I, Kaltashov IA. Platelet Factor 4 Interactions with Short Heparin Oligomers: Implications for Folding and Assembly Biophys J. 2020 Oct 6;119(7):1371-1379._x000D_ 4: Ataei S, Taheri MN, Tamaddon G, Behzad-Behbahani A, Taheri F, Rahimi A, Zare F, Amirian N. High-yield production of recombinant platelet factor 4 by harnessing and honing the gram-negative bacterial secretory apparatus PLoS One. 2020 May 7;15(5):e0232661._x000D_ 5: Rucinski B, Niewiarowski S, Strzyzewski M, Holt JC, Mayo KH. Human platelet factor 4 and its C-terminal peptides: heparin binding and clearance from the circulation Thromb Haemost. 1990 Jun 28;63(3):493-8._x000D_ 6: Foss B, Ulvestad E, Bruserud √ò. Platelet-derived growth factor (PDGF) in human acute myelogenous leukemia: PDGF receptor expression, endogenous PDGF release and responsiveness to exogenous PDGF isoforms by in vitro cultured acute myelogenous leukemia blasts Eur J Haematol. 2001 Oct;67(4):267-78._x000D_ 7: Park KS, Rifat S, Eck H, Adachi K, Surrey S, Poncz M. Biologic and biochemic properties of recombinant platelet factor 4 demonstrate identity with the native protein Blood. 1990 Mar 15;75(6):1290-5._x000D_ 8: Han Z, Shen Q, Han Z. [Bioassay of recombinant human platelet factor 4] Zhonghua Xue Ye Xue Za Zhi. 1997 Mar;18(3):123-5._x000D_ 9: St Charles R, Walz DA, Edwards BF. The three-dimensional structure of bovine platelet factor 4 at 3.0-A resolution J Biol Chem. 1989 Feb 5;264(4):2092-9._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/11488935">10: Foss B, Ulvestad E, Bruserud O. Platelet-derived growth factor (PDGF) in human acute myelogenous leukemia: PDGF receptor expression, endogenous PDGF release and responsiveness to exogenous PDGF isoforms by in vitro cultured acute myelogenous leukemia blasts Eur J Haematol. 2001 Jun;66(6):365-76. </a>_x000D_ _x000D_ <strong>Products Related to Human Platelet Factor 4 Native can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>