Recombinant Human IL-28B Protein

<strong>Recombinant Human IL-28B Protein</strong>_x000D_ <strong>Catalog number:</strong> B2015903_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 24 kDa, monomer, non-glycosylated_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> Cytokine Zcyto22, IFN lambda 3, IFN lambda 4, IFNL3, IFNL4, IFN-lambda 3, IFN-lambda 4, IL 28B, IL 28C_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Pestka S, Krause CD, Walter MR. Interferons, interferon-like cytokines, and their receptors Immunol Rev. 2004 Dec;202:8-32._x000D_ 2: Egli A, Santer DM, O'Shea D, Barakat K, Syedbasha M, Vollmer M, Baluch A, Bhat R, Groenendyk J, Joyce MA, Lisboa LF, Thomas BS, Battegay M, Khanna N, Mueller T, Tyrrell DL, Houghton M, Humar A, Kumar D. IL-28B is a key regulator of B- and T-cell vaccine responses against influenza PLoS Pathog. 2014 Dec 11;10(12):e1004556._x000D_ 3: Lu Y, Li L, Chen W, Wu M. Enhanced Anti-Tumor (Anti-Proliferation) Activity of Recombinant Human Interleukin-29 (IL-29) Mutants Using Site-Directed Mutagenesis Method Appl Biochem Biotechnol. 2015 Nov;177(5):1164-75._x000D_ 4: Terashima T, Honda M, Toyama T, Shimakami T, Shimizu R, Takatori H, Arai K, Kawaguchi K, Kitamura K, Yamashita T, Sakai Y, Yamashita T, Mizukoshi E, Kaneko S. IL-28B variant as a predictor in patients with advanced hepatocellular carcinoma treated with hepatic arterial infusion chemotherapy J Gastroenterol Hepatol. 2020 Oct;35(10):1813-1820._x000D_ 5: Luo Y, Ma X, Liu X, Lu X, Niu H, Yu H, Bai C, Peng J, Xian Q, Wang Y, Zhu B. IL-28B down-regulates regulatory T cells but does not improve the protective immunity following tuberculosis subunit vaccine immunization Int Immunol. 2016 Feb;28(2):77-85._x000D_ 6: Halfon P, Cacoub P. [IL-28B polymorphism and hepatitis C: impact on viral clearance--prolonged, spontaneous and after treatment with antiviral drugs] Rev Med Interne. 2011 May;32(5):271-4._x000D_ 7: Megjugorac NJ, Gallagher GE, Gallagher G. IL-4 enhances IFN-lambda1 (IL-29) production by plasmacytoid DCs via monocyte secretion of IL-1Ra Blood. 2010 May 27;115(21):4185-90._x000D_ 8: Rangnekar AS, Fontana RJ. Meta-analysis: IL-28B genotype and sustained viral clearance in HCV genotype 1 patients Aliment Pharmacol Ther. 2012 Jul;36(2):104-14._x000D_ 9: Sheppard P, Kindsvogel W, Xu W, Henderson K, Schlutsmeyer S, Whitmore TE, Kuestner R, Garrigues U, Birks C, Roraback J, Ostrander C, Dong D, Shin J, Presnell S, Fox B, Haldeman B, Cooper E, Taft D, Gilbert T, Grant FJ, Tackett M, Krivan W, McKnight G, Clegg C, Foster D, Klucher KM. IL-28, IL-29 and their class II cytokine receptor IL-28R Nat Immunol. 2003 Jan;4(1):63-8._x000D_ <a>10: Li MC, Wang HY, Wang HY, Li T, He SH. Liposome-mediated IL-28 and IL-29 expression in A549 cells and anti-viral effect of IL-28 and IL-29 on WISH cells Acta Pharmacol Sin. 2006 Apr;27(4):453-9. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant Human IL-28B Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>