µ-Conotoxin SIIIA

Product Specifications

CAS Number

[877860-32-7]

UNSPSC Description

μ-Conotoxin SIIIA is a tetrodotoxin (TTX)-resistant sodium channel blocker. μ-Conotoxin SIIIA is a toxic peptide that can be obtained from the venom of Conus snails. μ-Conotoxin SIIIA can be used in the study of neurological diseases, such as neuropathic pain[1].

Target Antigen

Sodium Channel

Type

Peptides

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Solubility

10 mM in DMSO

Smiles

O=C1N(C(N[C@@H](CC(N)=O)C(NC(CSSC[C@H](NC2=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(O)=O)C(N[C@@H](CC3=CNC=N3)C(N[C@@H](C)C(N[C@H]4CCCNC(N)=N)=O)=O)=O)=O)=O)C(N[C@@H](CSSC[C@@H]5NC4=O)C(N[C@@H](CC(N)=O)C(NCC(NCC(N[C@@H](CSSCC(NC5=O)C(N)=O)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@H]2CC6=CNC7=CC=CC=C67)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC1

Molecular Weight

2207.46

References & Citations

[1]Bulaj G, et al. Novel conotoxins from Conus striatus and Conus kinoshitai selectively block TTX-resistant sodium channels. Biochemistry. 2005 May 17;44(19):7259-65.