Bevenopran
Bevenopran is a peripheral μ-opioid receptor antagonist[1][2].
Product Specifications
CAS Number
676500-67-7
Product Name Alternative
CB-5945; ADL-5945
UNSPSC
12352005
Target
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Bevenopran.html
Concentration
10mM
Purity
99.09
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=NC=C(OC2=CC=C(CNCCC3CCOCC3)C=C2OC)N=C1)N
Molecular Formula
C20H26N4O4
Molecular Weight
386.44
References & Citations
[1]Diego L, et al. Novel opioid antagonists for opioid-induced bowel dysfunction. Expert Opin Investig Drugs. 2011 Aug;20 (8) :1047-56.|[2]Siemens W, et al. Advances in pharmacotherapy for opioid-induced constipation - a systematic review. Expert Opin Pharmacother. 2015 Mar;16 (4) :515-32.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
μ Opioid Receptor/MOR
Available Sizes
Frequently Asked Questions
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