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Bevenopran

Bevenopran is a peripheral μ-opioid receptor antagonist[1][2].

Product Specifications

CAS Number

[676500-67-7]

Product Name Alternative

CB-5945; ADL-5945

UNSPSC

12352005

Target

Opioid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Bevenopran.html

Concentration

10mM

Purity

99.09

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(C1=NC=C(OC2=CC=C(CNCCC3CCOCC3)C=C2OC)N=C1)N

Molecular Formula

C20H26N4O4

Molecular Weight

386.44

References & Citations

[1]Diego L, et al. Novel opioid antagonists for opioid-induced bowel dysfunction. Expert Opin Investig Drugs. 2011 Aug;20 (8) :1047-56.|[2]Siemens W, et al. Advances in pharmacotherapy for opioid-induced constipation - a systematic review. Expert Opin Pharmacother. 2015 Mar;16 (4) :515-32.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 3

Isoform

μ Opioid Receptor/MOR

Available Sizes

Curated Selection

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