Rhein-8-glucoside (calcium)
Rhein-8-glucoside calcium, an anthraquinone compound, is isolated from the EtOH extract of the roots of Saussurea lappa. Rhein-8-glucoside calcium is an hPTP1B inhibitor, with an IC50 of 11.5 μM. Rhein-8-glucoside calcium has antibacterial effects[1][2].
Product Specifications
CAS Number
113443-70-2
UNSPSC
12352005
Target
Bacterial; Phosphatase
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/rhein-8-glucoside-calcium.html
Solubility
10 mM in DMSO
Smiles
O=C(C(C=C1C2=O)=CC([O-])=C1C(C3=C2C([C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)=CC=C3O)=O)[O-].[Ca+2]
Molecular Formula
C21H16CaO11
Molecular Weight
484.42
References & Citations
[1]Li S, et, al. PTP1B inhibitors from Saussrurea lappa. J Asian Nat Prod Res. Apr-May 2006;8 (3) :281-6.|[2]Zhang Y, et, al. Effects of Rhein-8-O-β-D-glucopyranoside on the Biofilm Formation of Streptococcus mutans. Curr Microbiol. 2020 Oct 31.|[3]Zhang LS, et, al. Rhein-8-O-β-D-glucopyranoside inhibited high glucose-induced apoptosis of human mesangial cells by regulating the lincRNA ANRIL/let-7a/TGF-β1/Smad signaling pathway. Exp Ther Med. 2020 Apr;19 (4) :2871-2878.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC740745-500 1x 500 µL
CD45 / LCA (2B11 + PD7/26), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC470050-100 1x 100 µL
IgA Secretory Component (SC05), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040146-500 1x 500 µL
CD10 (CB-CALLA), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400226-100 1x 100 µL
Pmel17 / gp100 / SILV (NKI-beteb), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
