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8-Chloro-cAMP

8-Chloro-cAMP is a cAMP analogue that induces growth arrest, and modulates cAMP-dependent PKA activity. 8-Chloro-cAMP has anticancer activity[1].

Product Specifications

CAS Number

41941-56-4

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PKA

Type

Reference compound

Related Pathways

Stem Cell/Wnt; TGF-beta/Smad

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/8-chloro-camp.html

Purity

99.0

Solubility

10 mM in DMSO

Smiles

NC1=NC=NC2=C1N=C(Cl)N2[C@H]3[C@H](O)[C@H](O4)[C@@H](COP4(O)=O)O3

Molecular Formula

C10H11ClN5O6P

Molecular Weight

363.65

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]C Indolfi, et al. 8-chloro-cAMP inhibits smooth muscle cell proliferation in vitro and neointima formation induced by balloon injury in vivo. J Am Coll Cardiol. 2000 Jul;36 (1) :288-93.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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