Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

STAT3-IN-17

STAT3-IN-17 is a moderate STAT3 inhibitor (IC50=0.7 μM; HEK-Blue IL-6), with antiproliferative activity in HeLa cells. STAT3-IN-17 has good pharmacokinetic characteristics. STAT3-IN-17 also inhibits pyruvate-ferredoxin oxidoreductase (PFOR), and inhibits Helicobacter pylori[1][2].

Product Specifications

CAS Number

1245814-52-1

UNSPSC

12352005

Target

STAT

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/stat3-in-17.html

Purity

98.0

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(NC1=NC=C([N+]([O-])=O)S1)C2=CC=C(C(F)(F)F)C=C2

Molecular Formula

C11H6F3N3O3S

Molecular Weight

317.24

References & Citations

[1]Lü Z, et al. Structure-Activity Study of Nitazoxanide Derivatives as Novel STAT3 Pathway Inhibitors. ACS Med Chem Lett. 2021 Apr 1;12 (5) :696-703.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

STAT3

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

CD33 Recombinant Rabbit Monoclonal Antibody [PSH02-51]
HA721827 100 µL

CD33 Recombinant Rabbit Monoclonal Antibody [PSH02-51]

Sign In for Pricing
View Details
6-Chloro-8-quinolinecarboxylic Acid
TRC-C379910-50MG 50 mg

6-Chloro-8-quinolinecarboxylic Acid

Sign In for Pricing
View Details
Elab Bright™ Violet 510 Anti-Mouse CD86 Antibody[GL-1]
E-AB-F0994R1 50 Tests

Elab Bright™ Violet 510 Anti-Mouse CD86 Antibody[GL-1]

Sign In for Pricing
View Details
REX1BD (NM_001100419) Human Over-expression Lysate
LY420258 100 µg

REX1BD (NM_001100419) Human Over-expression Lysate

Sign In for Pricing
View Details
Human LRRC8A activation kit by CRISPRa
GA111171 1 Kit

Human LRRC8A activation kit by CRISPRa

Sign In for Pricing
View Details
Lysinoalanine Hydrochloride Salt
TRC-L488650-5MG 5 mg

Lysinoalanine Hydrochloride Salt

Sign In for Pricing
View Details