Uridine-5'-O-(3-thiotriphosphate)
Product Specifications
UNSPSC Description
Uridine-5'-O-(3-thiotriphosphate) (UTPγS), a stable analogue of UTP, is a potent agonist of the P2Y2 and P2Y4 receptors with increased metabolic stability[1][2].
Target Antigen
P2Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/uridine-5-o-3-thiotriphosphate.html
Smiles
O[C@H]1[C@@H](O)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1COP(OP(OP(O)(S)=O)(O)=O)(O)=O
Molecular Weight
500.21
References & Citations
[1]Anna-Karin Wihlborg, et al. Positive inotropic effects by uridine triphosphate (UTP) and uridine diphosphate (UDP) via P2Y2 and P2Y6 receptors on cardiomyocytes and release of UTP in man during myocardial infarction. Circ Res. 2006 Apr 14;98(7):970-6.|[2]Malin Malmsjö, et al. The stable pyrimidines UDPβS and UTPγS discriminate between the P2 receptors that mediate vascular contraction and relaxation of the rat mesenteric artery. Br J Pharmacol. 2000 Sep;131(1):51-6.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-137603/Uridine-5-O-3-thiotriphosphate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-137603/
Clinical Information
No Development Reported
CAS Number
79049-97-1
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