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Sesame Oil

Sesame Oil is a vegetable oil. Sesame Oil can be extracted from the seeds of Sesamum indicum L. Sesame Oil decreases NF-κB, aspartate aminotransferase, alanine aminotransferase, IL-1β, IL-4 and nitric oxide. Sesame Oil has antitumor activity against malignant melanoma. Sesame Oil has protective effects against liver damage caused by various agents such as Cisplatin and Acetaminophen (HY-66005). Sesame Oil shows antinociceptive and anti-inflammatory activities[1][2][3][4][5][6][7][8].

Product Specifications

CAS Number

8008-74-0

UNSPSC

12352211

Target

Aminotransferases (Transaminases) ; Biochemical Assay Reagents; Interleukin Related; NF-κB; NO Synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sesame-oil.html

Purity

98.0

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

[SesameOil]

References & Citations

[1]Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.|[2]Smith DE, et al. Selective growth inhibition of a human malignant melanoma cell line by sesame oil in vitro. Prostaglandins Leukot Essent Fatty Acids. 1992 Jun;46 (2) :145-50.|[3]Hsu DZ, et al. Therapeutic effects of sesame oil on monosodium urate crystal-induced acute inflammatory response in rats. Springerplus. 2013 Dec 7;2:659.|[4]Hsu DZ, et al. Effects of sesame oil on oxidative stress after the onset of sepsis in rats. Shock. 2004 Dec;22 (6) :582-5.|[5]Monteiro EM, et al. Antinociceptive and anti-inflammatory activities of the sesame oil and sesamin. Nutrients. 2014 May 12;6 (5) :1931-44.|[6]Hsu DZ, et al. Sesame oil attenuates Cisplatin-induced hepatic and renal injuries by inhibiting nitric oxide-associated lipid peroxidation in mice. Shock. 2007 Feb;27 (2) :199-204.|[7]Chandrasekaran VR, et al. Effects of sesame oil against after the onset of acetaminophen-induced acute hepatic injury in rats. JPEN J Parenter Enteral Nutr. 2010 Sep-Oct;34 (5) :567-73.|[8]Hsu DZ, et al. Sesame oil protects against lead-plus-lipopolysaccharide-induced acute hepatic injury. Shock. 2007 Mar;27 (3) :334-7.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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