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Azilsartan mepixetil-d5

Azilsartan mepixetil-d5 (QR-01019-d5) is deuterium labeled Azilsartan mepixetil. Azilsartan mepixetil is the antagonist of angiotensin II receptor. Azilsartan mepixetil has stronger and longer blood pressure effect, more abvious and longer lasting heart rate lowering effect and high safety. Azilsartan mepixetil achieves ideal protective effect for heart and kidney functions. Azilsartan mepixetil has the potential for the research of hypertension, chronic heart failure and diabetic nephropathy (extracted from patent CN107400122A) [1][2].

Product Specifications

Product Name Alternative

QR-01019-d5

UNSPSC

12352005

Target

Angiotensin Receptor; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Others

Field of Research

Cardiovascular Disease

Smiles

O=C1NC(C2=CC=CC=C2C(C=C3)=CC=C3CN4C(OC(C([2H])([2H])[2H])([2H])[2H])=NC5=CC=CC(C(OC(OC(OCC6=NC(C)=C(C)N=C6C)=O)C)=O)=C54)=NO1

Molecular Formula

C36H29D5N6O8

Molecular Weight

683.72

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Ma, Jianyi, et al. Compound and preparation method thereof, composition and application. Patent CN107400122A.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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