GSK3117391
GSK3117391 (ESM-HDAC391) is a histone deacetylase (HDAC) inhibitor, extracted from patent WO/2008040934 A1. Target: HDAC
Product Specifications
CAS Number
1018673-42-1
Product Name Alternative
ESM-HDAC391; CHR-5154; HDAC-IN-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/HDAC-IN-3.html
Purity
99.40
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C([C@@H](NCC1=CN=C(CCC(NO)=O)C=C1)C2CCCCC2)OC3CCCC3
Molecular Formula
C22H33N3O4
Molecular Weight
403.52
Precautions
H302, H315, H319, H335
References & Citations
[1]Davidson Alan Hornsby, et al. Preparation of amino acid-based hydroxamic acids as histone deacetylase (HDAC) inhibitors. From PCT Int. Appl. (2008), WO 2008040934 A1 20080410.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
HDAC
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
032161-ML550 100 µL
ATF4, ID (ATF4, CREB2, TXREB, Cyclic AMP-dependent transcription factor ATF-4, Activating transcription factor 4, Cyclic AMP-responsive element-binding protein 2, DNA-binding protein TAXREB67, Tax-responsive enhancer element-binding protein 67) (MaxLight 550) discontinued
Sign In for Pricing
View Details 
TL705877V 500 µL Each
Spock3 Rat shRNA Lentiviral Particle (Locus ID 306404)
Sign In for Pricing
View Details 