Acazicolcept
Acazicolcept (ALPN-101), an Fc fusion protein, is a dual inducible T cell costimulator (ICOS) /CD28 antagonist. Acazicolcept has anti-inflammatory activities[1].
Product Specifications
CAS Number
[2797026-97-0]
Product Name Alternative
ALPN-101
UNSPSC
12352203
Target
CD28
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/acazicolcept.html
Purity
99.27
Solubility
10 mM in DMSO
Smiles
[Acazicolcept]
Molecular Weight
(80.82 kDa)
References & Citations
[1]Cindy Orvain, et al. Acazicolcept (ALPN-101), a dual ICOS/CD28 antagonist, demonstrates efficacy in systemic sclerosis preclinical mouse models. Arthritis Res Ther. 2022 Jan 5;24 (1) :13.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2
Available Sizes
Curated Selection
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