L 363851
Product Specifications
UNSPSC Description
L 363851 is a Neurokinin 2 receptor agonist, and induces the contractile response of tracheal smooth muscle devoid of epithelium (IC50 of 3.2 nM) and phosphoinositide hydrolysis (IC50 of 36 μM).
Target Antigen
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/l-363851.html
Smiles
CSCC[C@@H](C(N)=O)NC([C@@H](N1C([C@@H](CC1)NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@@H]3CCC(N3)=O)=O)CC4=CC=CC=C4)=O)=O)=O)CC(C)C)=O
Molecular Weight
749.92
References & Citations
[1]Grandordy BM, et al. Tachykinin-induced phosphoinositide breakdown in airway smooth muscle and epithelium: relationship to contraction. Mol Pharmacol. 1988;33(5):515-519.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-125304/L-363851-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-125304/
Clinical Information
No Development Reported
CAS Number
100807-53-2
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