L 363851
L 363851 is a Neurokinin 2 receptor agonist, and induces the contractile response of tracheal smooth muscle devoid of epithelium (IC50 of 3.2 nM) and phosphoinositide hydrolysis (IC50 of 36 μM) .
Product Specifications
CAS Number
[100807-53-2]
UNSPSC
12352005
Target
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/l-363851.html
Smiles
CSCC[C@@H](C(N)=O)NC([C@@H](N1C([C@@H](CC1)NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@@H]3CCC(N3)=O)=O)CC4=CC=CC=C4)=O)=O)=O)CC(C)C)=O
Molecular Formula
C38H51N7O7S
Molecular Weight
749.92
References & Citations
[1]Grandordy BM, et al. Tachykinin-induced phosphoinositide breakdown in airway smooth muscle and epithelium: relationship to contraction. Mol Pharmacol. 1988;33 (5) :515-519.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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