Cryptomeridiol
Cryptomeridiol is a platelet-activating factor (PAF) receptor binding inhibitor. Cryptomeridiol has melanogenesis inhibitory activity in the α-MSH -stimulated B16 melanoma cells[1][2].
Product Specifications
CAS Number
4666-84-6
UNSPSC
12352211
Target
Platelet-activating Factor Receptor (PAFR)
Type
Natural Products
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cryptomeridiol.html
Solubility
10 mM in DMSO
Smiles
C[C@]12[C@@]([C@](O)(CCC2)C)([H])C[C@@H](CC1)C(C)(O)C
Molecular Formula
C15H28O2
Molecular Weight
240.38
References & Citations
[1]Kikuchi T, et al. Melanogenesis inhibitory activity of sesquiterpenes from Canarium ovatum resin in mouse B16 melanoma cells. Chem Biodivers. 2012 Aug;9 (8) :1500-7.|[2]Bushra Abdulkarim Moharam, et al. Inhibitory effect of compounds from Goniothalamus tapis Miq. and Goniothalamus uvaroides King on platelet-activating factor receptor binding. Phytother Res. 2012 May;26 (5) :687-91.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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