Lignoceric acid

Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2].

Product Specifications

CAS Number

[557-59-5]

Product Name Alternative

Tetracosanoic acid

UNSPSC

12352211

Hazard Statement

H315, H319

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/lignoceric-acid.html

Purity

98.80

Solubility

THF : 25 mg/mL (ultrasonic)

Smiles

CCCCCCCCCCCCCCCCCCCCCCCC(O)=O

Molecular Formula

C24H48O2

Molecular Weight

368.64

Precautions

H315, H319

References & Citations

[1]Anna Petroni, et al. Thermogenic flux induced by lignoceric acid in peroxisomes isolated from HepG2 cells and from X-adrenoleukodystrophy and control fibroblasts. J Cell Physiol. 2019 Aug;234 (10) :18344-18348.|[2]J M Bourre, et al. Lignoceric acid biosynthesis in the developing brain. Activities of mitochondrial acetyl-CoA-dependent synthesis and microsomal malonyl-CoA chain-elongating system in relation to myelination. Comparison between normal mouse and dysmyelinating mutants (quaking and jimpy) . Eur J Biochem. 1977 Jan 3;72 (1) :41-7.