Cirsilineol (Standard)
Product Specifications
UNSPSC Description
Cirsilineol (Standard) is the analytical standard of Cirsilineol. This product is intended for research and analytical applications. Cirsilineol, a natural flavone compound, selectively inhibits IFN-γ/STAT1/T-bet signaling in intestinal CD4+ T cells. Cirsilineol has potent immunosuppressive and anti-tumor properties. Cirsilineol significantly ameliorates trinitro-benzene sulfonic acid (TNBS)-induced T-cell-mediated experimental colitis in mice[1].
Target Antigen
IFNAR; STAT
Type
Reference Standards
Related Pathways
Immunology/Inflammation;JAK/STAT Signaling;Stem Cell/Wnt
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cirsilineol-standard.html
Smiles
O=C1C=C(OC2=CC(OC)=C(C(O)=C12)OC)C3=CC=C(C(OC)=C3)O
Molecular Weight
344.32
References & Citations
[1]Yang Sun, et al. Novel immunomodulatory properties of cirsilineol through selective inhibition of IFN-gamma signaling in a murine model of inflammatory bowel disease. Biochem Pharmacol. 2010 Jan 15;79(2):229-38.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-119347R/Cirsilineol-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-119347R/
CAS Number
41365-32-6
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1163787-01 0.02 mg (E-Coli)
Recombinant Mycobacterium tuberculosis Proteasome subunit beta (prcB)
Ask
View Details 
MBS1163787-02 0.1 mg (E-Coli)
Recombinant Mycobacterium tuberculosis Proteasome subunit beta (prcB)
Ask
View Details 
MBS1163787-03 0.02 mg (Yeast)
Recombinant Mycobacterium tuberculosis Proteasome subunit beta (prcB)
Ask
View Details MBS1163787-04 0.1 mg (Yeast)
Recombinant Mycobacterium tuberculosis Proteasome subunit beta (prcB)
Ask
View Details MBS1163787-05 0.02 mg (Baculovirus)
Recombinant Mycobacterium tuberculosis Proteasome subunit beta (prcB)
Ask
View Details MBS1163787-06 0.02 mg (Mammalian-Cell)
Recombinant Mycobacterium tuberculosis Proteasome subunit beta (prcB)
Ask
View Details