TX-1918
TX-1918 is an inhibitor for eukaryotic elongation factor 2 kinase (eEF2-K) and Src kinase with IC50 of 0.44 and 4.4 μM, respectively. TX-1918 exhibits cytotoxicity in cell HepG2 and HCT116, with IC50 of 2.07 and 230 μM, respectively. TX-1918 inhibits the C-terminal domain of HIV-1 CA (CA CTD) (IC50 =3.81 μM), and inhibits the viral replication (IC50 =15.16 μM) [1][2].
Product Specifications
CAS Number
503473-32-3
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
HIV; PKA; PKC; Src
Type
Reference compound
Related Pathways
Anti-infection; Epigenetics; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt; TGF-beta/Smad
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/tx-1918.html
Smiles
O=C1/C(C(C=C1)=O)=C\C2=CC(C)=C(O)C(C)=C2
Molecular Formula
C14H12O3
Molecular Weight
228.24
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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