2,5-Dihydroxybenzoic acid

2,5-Dihydroxybenzoic acid is a derivative of benzoic and a powerful inhibitor of fibroblast growth factors.

Product Specifications

CAS Number

[490-79-9]

Product Name Alternative

Gentisic acid

UNSPSC

12352005

Hazard Statement

H302

Target

Endogenous Metabolite; FGFR

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/2,5-Dihydroxybenzoic_acid.html

Purity

99.97

Solubility

DMSO : ≥ 100 mg/mL|H2O : 7.14 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OC(C=C1)=C(C(O)=O)C=C1O

Molecular Formula

C7H6O4

Molecular Weight

154.12

Precautions

H302

References & Citations

[1]Levy G, et al. Salicylate accumulation kinetics in man. N Engl J Med. 1972 Aug 31;287 (9) :430-2.|[2]IS Fernández, et al. Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors. Journal of Biological Chemistry , 2010, 285 (15) :11714-29.