2,5-Dihydroxybenzoic acid
2,5-Dihydroxybenzoic acid is a derivative of benzoic and a powerful inhibitor of fibroblast growth factors.
Product Specifications
CAS Number
490-79-9
Product Name Alternative
Gentisic acid
UNSPSC
12352005
Hazard Statement
H302
Target
Endogenous Metabolite; FGFR
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/2,5-Dihydroxybenzoic_acid.html
Purity
99.97
Solubility
DMSO : ≥ 100 mg/mL|H2O : 7.14 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OC(C=C1)=C(C(O)=O)C=C1O
Molecular Formula
C7H6O4
Molecular Weight
154.12
Precautions
H302
References & Citations
[1]Levy G, et al. Salicylate accumulation kinetics in man. N Engl J Med. 1972 Aug 31;287 (9) :430-2.|[2]IS Fernández, et al. Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors. Journal of Biological Chemistry , 2010, 285 (15) :11714-29.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite; Microbial Metabolite
Available Sizes
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