Mequindox
Mequindox is an antimicrobial agent[1]. Mequindox acts as an inhibitor of DNA synthesis. Mequindox induces genotoxicity and carcinogenicity in mice[2].
Product Specifications
CAS Number
[13297-17-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bacterial; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mequindox.html
Concentration
10mM
Purity
99.62
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C1=C(C)[N+]([O-])=C2C=CC=CC2=[N+]1[O-])=O
Molecular Formula
C11H10N2O3
Molecular Weight
218.21
Precautions
H302, H315, H319, H335
References & Citations
[1]Qianying Liu, et al. Mequindox Induced Genotoxicity and Carcinogenicity in Mice. Front Pharmacol. 2018 Apr 10;9:361.|[2]Qianying Liu, et al. Mequindox-Induced Kidney Toxicity Is Associated With Oxidative Stress and Apoptosis in the Mouse. Front Pharmacol. 2018 May 1;9:436.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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