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Jedi2

Product Specifications

UNSPSC Description

Jedi2 is a Piezo1 activator, but not a specific Piezo2 activator. Jedi2 binds to the mouse Piezo1 proteins with a Kd of 2770??μM[1].

Target Antigen

Piezo Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/jedi2.html

Purity

99.93

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C1=C(C)OC(C2=CC=CS2)=C1)O

Molecular Weight

208.23

References & Citations

[1]Yanfeng Wang, et al. A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel. Nat Commun. 2018 Apr 3;9(1):1300.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-131018/Jedi2-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-131018/Jedi2-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

651005-90-2

Available Sizes

Curated Selection

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