Calcium channel-modulator-1
Calcium channel-modulator-1 is an orally active calcium channel modulator that blocks aortic contraction with an IC50 of 0.8 μM. Calcium channel-modulator-1 can be used for the study of cardiovascular conditions[1].
Product Specifications
CAS Number
[136941-70-3]
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/3,5-Pyridinedicarboxylic_acid,_4-_2,3-dichlorophenyl_-1,4-dihydro-2,6-dimethyl-,_methyl_3-_3-oxo-1,2-benzisothiazol-2_3H_-yl_propyl_ester,_S,S-dioxide.html
Concentration
10mM
Purity
98.77
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC=CC(Cl)=C2Cl)OCCCN(C(C3=C4C=CC=C3)=O)S4(=O)=O
Molecular Formula
C26H24Cl2N2O7S
Molecular Weight
579.45
References & Citations
[1]Sunkel CE, et al. Synthesis of 3-[ (2,3-dihydro-1,1,3-trioxo-1,2-benzisothiazol-2-yl) alkyl] 1,4-dihydropyridine-3,5-dicarboxylate derivatives as calcium channel modulators. J Med Chem. 1992 Jun 26;35 (13) :2407-14.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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