NCGC00188636
NCGC00188636 is a novel covalent pyruvate kinase (PYK) inhibitor. NCGC00188636 blocks nucleotide binding to the active site of pyruvate kinase. NCGC00188636 can be used for the research of the metabolism of many organisms and cell types.
Product Specifications
CAS Number
[1039980-33-0]
UNSPSC
12352005
Target
Pyk2
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ncgc00188636.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
O=C(O)C1=CC=CC=C1SC(C2=C3C=CC=C2)=NS3(=O)=O
Molecular Formula
C14H9NO4S2
Molecular Weight
319.36
References & Citations
[1]Hugh P Morgan, et al. A new family of covalent inhibitors block nucleotide binding to the active site of pyruvate kinase. Biochem J. 2012 Nov 15;448 (1) :67-72.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
123733 100 µg
ATP6V1E1 (V-type Proton ATPase Subunit E 1, V-ATPase Subunit E 1, V-ATPase 31kD Subunit, p31, Vacuolar Proton Pump Subunit E 1, ATP6E, ATP6E2)
Sign In for Pricing
View Details 
MBS6373574-01 0.1 mL
CDK7 (Cell Division Protein Kinase 7, CDK-activating Kinase, CAK, TFIIH Basal Transcription Factor Complex Kinase Subunit, 39kD Protein Kinase, P39 Mo15, STK1, CAK1, MO15) (MaxLight 750)
Sign In for Pricing
View Details 
MBS6373574-02 5x 0.1 mL
CDK7 (Cell Division Protein Kinase 7, CDK-activating Kinase, CAK, TFIIH Basal Transcription Factor Complex Kinase Subunit, 39kD Protein Kinase, P39 Mo15, STK1, CAK1, MO15) (MaxLight 750)
Sign In for Pricing
View Details K1460305 3x 1.0 µg
NT5E sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
Sign In for Pricing
View Details RDR-BAFF-Ra-48Tests 48 Tests
Rat B-Cell Activating Factor (BAFF) ELISA Kit
Sign In for Pricing
View Details