NCGC00188636
Product Specifications
UNSPSC Description
NCGC00188636 is a novel covalent pyruvate kinase (PYK) inhibitor. NCGC00188636 blocks nucleotide binding to the active site of pyruvate kinase. NCGC00188636 can be used for the research of the metabolism of many organisms and cell types.
Target Antigen
Pyk2
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ncgc00188636.html
Smiles
O=C(O)C1=CC=CC=C1SC(C2=C3C=CC=C2)=NS3(=O)=O
Molecular Weight
319.36
References & Citations
[1]Hugh P Morgan, et al. A new family of covalent inhibitors block nucleotide binding to the active site of pyruvate kinase. Biochem J. 2012 Nov 15;448(1):67-72.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-138825/NCGC00188636-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-138825/NCGC00188636-SDS-MedChemExpress.pdf
CAS Number
1039980-33-0
Available Sizes
Curated Selection
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