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NR2E3 agonist 1

Product Specifications

UNSPSC Description

NR2E3 agonist 1 (Compound 11a) is a small molecule agonist of the photoreceptor-specific nuclear receptor (NR2E3) with an EC50 value of less than 200 nM. NR2E3 agonist 1 can be used in retinitis pigmentosa research[1].

Target Antigen

Others

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/nr2e3-agonist-1.html

Solubility

10 mM in DMSO

Smiles

O=C(C1CC1)NC2=CC=C(NC(C3=CC=C(NC(C4=CC=CC=C4Cl)=O)C=C3)=N5)C5=C2

Molecular Weight

430.89

References & Citations

[1]Wolkenberg SE, et al. Identification of potent agonists of photoreceptor-specific nuclear receptor (NR2E3) and preparation of a radioligand. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5001-4.

Shipping Conditions

Blue Ice

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-161115/NR2E3-agonist-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-161115/NR2E3-agonist-1-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

911211-69-3

Available Sizes

Curated Selection

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