HSP10/EPF, Goat/Human/Mouse (His-Avi)

The HSP10/EPF protein in collaboration with Hsp60 promotes the correct folding of the input protein and, under stressful conditions in the mitochondrial matrix, prevents misfolding while promoting the refolding and correct assembly of the unfolded polypeptide. The increased expression of HSP10 protein can inhibit the apoptosis of astrocytoma cells and is associated with poor prognosis. HSP10/EPF Protein, Goat/Human/Mouse (His-Avi) is the recombinant human, mouse-derived HSP10/EPF protein, expressed by E. coli , with C-Avi, N-His labeled tag.

Product Specifications

Product Name Alternative

HSP10/EPF Protein, Goat/Human/Mouse (His-Avi), Human; Mouse, E. coli

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/hsp10-epf-protein-human-mouse-his-avi.html

Molecular Formula

102173048 (Gene_ID) A0A8C2NRB8/XP_005676362 (A2-D102) (Accession)

Molecular Weight

Approximately 13.7 kDa, based on SDS-PAGE under reducing conditions.

References & Citations

[1]David S, et al. Hsp10: anatomic distribution, functions, and involvement in human disease. Front Biosci (Elite Ed) . 2013 Jan 1;5 (2) :768-78.|[2]Fucarino A, et al. Role of HSP60/HSP10 in Lung Cancer: Simple Biomarkers or Leading Actors? J Oncol. 2020 Mar 30;2020:4701868.|[3]Fan W, et al. Elevated expression of HSP10 protein inhibits apoptosis and associates with poor prognosis of astrocytoma. PLoS One. 2017 Oct 13;12 (10) :e0185563.