BLI-489

BLI-489 is a beta-lactamase inhibitor. BLI-489 combined with Piperacillin (HY-B1923) inhibits infection caused by class A (including ultra-broad spectrum β-lactamase), Class C (AmpC) and Class D β-lactamase expressing pathogens[1].

Product Specifications

CAS Number

[623564-40-9]

UNSPSC

12352005

Target

Bacterial; Beta-lactamase

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/bli-489.html

Purity

95.77

Solubility

DMSO : ≥ 105 mg/mL

Smiles

O=C(C1=CS[C@@](/C2=C/C3=CN4C(COCC4)=N3)([H])N1C2=O)O[Na]

Molecular Formula

C13H10N3NaO4S

Molecular Weight

327.29

References & Citations

[1]Wang YC, et al. In vitro and in vivo activities of imipenem combined with BLI-489 against class D β-lactamase-producing Acinetobacter baumannii. J Antimicrob Chemother. 2021;76 (2) :451-459.