α-Glucosidase-IN-68
Product Specifications
UNSPSC Description
α-Glucosidase-IN-68 (Compound 2) is an inhibitor for α-Glucosidase, AChE, and BChE, with IC50 of 0.251, 0.774 and 0.793 μM, respectively. α-Glucosidase-IN-68 exhibits antioxidant efficacy, with IC50 of 0.69 μM and 0.02 μM, in DPPH and ABTS experiments. α-Glucosidase-IN-68 exhibits antidiabetic effect in Streptozotocin (HY-13753)-induced diabetic rat models[1].
Target Antigen
Cholinesterase (ChE); Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease;Neuronal Signaling
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/α-glucosidase-in-68.html
Smiles
O=C(C1=C(NC2=CC=C(F)C=C2)CC(C3=CC=C(F)C=C3)N(C4=CC=C(F)C=C4)C1C5=CC=C(F)C=C5)OCC
Molecular Weight
546.55
References & Citations
[1]Mughal EU, et al., Exploring fluorine-substituted piperidines as potential therapeutics for diabetes mellitus and Alzheimer's diseases. Eur J Med Chem. 2024 Jul 5;273:116523.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162639/α-Glucosidase-IN-68-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162639/
Clinical Information
No Development Reported
CAS Number
1624628-01-8
Curated Selection
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