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α-Glucosidase-IN-68

α-Glucosidase-IN-68 (Compound 2) is an inhibitor for α-Glucosidase, AChE, and BChE, with IC50 of 0.251, 0.774 and 0.793 μM, respectively. α-Glucosidase-IN-68 exhibits antioxidant efficacy, with IC50 of 0.69 μM and 0.02 μM, in DPPH and ABTS experiments. α-Glucosidase-IN-68 exhibits antidiabetic effect in Streptozotocin (HY-13753) -induced diabetic rat models[1].

Product Specifications

CAS Number

[1624628-01-8]

UNSPSC

12352005

Target

Cholinesterase (ChE) ; Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/α-glucosidase-in-68.html

Smiles

O=C(C1=C(NC2=CC=C(F)C=C2)CC(C3=CC=C(F)C=C3)N(C4=CC=C(F)C=C4)C1C5=CC=C(F)C=C5)OCC

Molecular Formula

C32H26F4N2O2

Molecular Weight

546.55

References & Citations

[1]Mughal EU, et al., Exploring fluorine-substituted piperidines as potential therapeutics for diabetes mellitus and Alzheimer's diseases. Eur J Med Chem. 2024 Jul 5;273:116523.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

AChE; BChE

Curated Selection

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