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SCH-53870

SCH-53870 is a Ras activation inhibitor that binds to the Ras-GDP complex, keeping the Ras protein in an inactive GDP-bound state and preventing it from switching to an active GTP-bound state. SCH-53870 affects cell signaling and cell proliferation by preventing the activation of Ras protein. SCH-53870 can be used in cancer research[1].

Product Specifications

CAS Number

188480-50-4

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sch-53870.html

Smiles

O=S(C1=CC=C(NO)C=C1)(NCCOC2=CC=C3C=CC=CC3=C2)=O

Molecular Formula

C18H18N2O4S

Molecular Weight

358.41

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Colombo, et al. Design and characterization of a new class of inhibitors of ras activation. Annals of the New York Academy of Sciences 1030.1 (2004) : 52-61.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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