Antimycobacterial agent-4
Antimycobacterial agent-4 is a 2-amino-4- (2-pyridyl) thiazole derivative, with antimycobacterial activity, antiplasmodial activity, and cytotoxicity on a mammalian cell line[1][2].
Product Specifications
CAS Number
[476319-66-1]
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Bacterial; Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antimycobacterial-agent-4.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=NC(C2=NC=CC=C2)=CS1)C3=CC=C([N+]([O-])=O)C=C3
Molecular Formula
C15H10N4O3S
Molecular Weight
326.33
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Mjambili F, et al. Synthesis and biological evaluation of 2-aminothiazole derivatives as antimycobacterial and antiplasmodial agents. Bioorg Med Chem Lett. 2014 Jan 15;24 (2) :560-4. |[2]Kesicki EA, et al. Synthesis and Evaluation of the 2-Aminothiazoles as Anti-Tubercular Agents. PLoS One. 2016 May 12;11 (5) :e0155209.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Plasmodium
Available Sizes
Curated Selection
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