Antimycobacterial agent-4

Antimycobacterial agent-4 is a 2-amino-4- (2-pyridyl) thiazole derivative, with antimycobacterial activity, antiplasmodial activity, and cytotoxicity on a mammalian cell line[1][2].

Product Specifications

CAS Number

[476319-66-1]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

Bacterial; Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antimycobacterial-agent-4.html

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NC1=NC(C2=NC=CC=C2)=CS1)C3=CC=C([N+]([O-])=O)C=C3

Molecular Formula

C15H10N4O3S

Molecular Weight

326.33

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Mjambili F, et al. Synthesis and biological evaluation of 2-aminothiazole derivatives as antimycobacterial and antiplasmodial agents. Bioorg Med Chem Lett. 2014 Jan 15;24 (2) :560-4. |[2]Kesicki EA, et al. Synthesis and Evaluation of the 2-Aminothiazoles as Anti-Tubercular Agents. PLoS One. 2016 May 12;11 (5) :e0155209.