1,4-PBIT (dihydrobromide)
Product Specifications
UNSPSC Description
1,4-PBIT (1,4-PB-ITU) dihydrobromide (compound 46) is a potent nitric oxide synthases (NOS) inhibitor, with Ki values of 7.6 nM, 360 nM, and 16 nM for the inducible (iNOS), endothelial (eNOS), and neuronal (nNOS) isozymes, respectively[1].
Target Antigen
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/1-4-pbit-dihydrobromide.html
Smiles
NC(SCCC1=CC=C(CCSC(N)=N)C=C1)=N.[H]Br.[H]Br
Molecular Weight
444.25
References & Citations
[1]E P Garvey, et al. Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas. J Biol Chem. 1994 Oct 28;269(43):26669-76.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-135224/1-4-PBIT-dihydrobromide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-135224/
CAS Number
157254-60-9
Available Sizes
Curated Selection
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